- Size, Trend, Share, Opportunity Analysis, and Forecast, 2015-2026
The global ligase enzyme market was valued at $503 million in 2015, and is projected to reach $918 million by 2026, growing at a CAGR of 5.3% from 2018 to 2026.
An enzyme is a protein that acts as a catalyst to accelerate a chemical reaction without being consumed. Ligase is an enzyme, which is used to join the strands of DNA by facilitating the formation of phosphodiester bonds. The formation of phosphodiester bonds is facilitated by the simultaneous conversion of adenosine triphosphate (ATP) to adenosine diphosphate (ADP). Ligase is majorly used for repairing and replication of DNA strands. In addition, it finds its application in recombinant DNA experiments in molecular biology experiments. Moreover, it is used in cloning, mutation detection, gene synthesis, and next-generation sequencing.
Rise in research activities for sequencing applications and increase in incidence of birth genetic disorders & infectious diseases are the key factors that contribute toward the growth of the global ligases enzyme market. In addition, surge in R&D investments to develop ligases as therapeutic interventions of cancer fuels the market growth. However, high sensitivity of the enzyme to factors such as DNA concentration, ligase concentration, temperature, and buffer composition affect limits its adoption, thereby restraining the market growth.
Based on source, the global ligase enzyme market is segmented into microorganism, animal, and plant. Depending on end user, it is bifurcated into diagnostic center & hospital and research institute. Region wise, it is studied across North America (U.S., Canada, and Mexico), Europe (Germany, France, the UK, Italy, Spain, and rest of Europe), Asia-Pacific (Japan, China, Australia, India, South Korea, and rest of Asia-Pacific), and LAMEA (Brazil, Saudi Arabia, South Africa, and rest of LAMEA).
The major players profiled in the report include Novozymes A/S, Koninklijke DSM N.V., DowDuPont Inc., BASF SE, Advanced Enzyme Technologies Ltd., AB Enzymes GmbH, Codexis, Inc., Amano Enzyme, F. Hoffmann-La Roche Ltd., and Thermo Fisher Scientific Inc.
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