Global Ligase Enzyme Market Overview:

The global ligase enzyme market was valued at $503 million in 2015, and is projected to reach $918 million by 2026, growing at a CAGR of 5.3% from 2018 to 2026.

An enzyme is a protein that acts as a catalyst to accelerate a chemical reaction without being consumed. Ligase is an enzyme, which is used to join the strands of DNA by facilitating the formation of phosphodiester bonds. The formation of phosphodiester bonds is facilitated by the simultaneous conversion of adenosine triphosphate (ATP) to adenosine diphosphate (ADP). Ligase is majorly used for repairing and replication of DNA strands. In addition, it finds its application in recombinant DNA experiments in molecular biology experiments. Moreover, it is used in cloning, mutation detection, gene synthesis, and next-generation sequencing.

Rise in research activities for sequencing applications and increase in incidence of birth genetic disorders & infectious diseases are the key factors that contribute toward the growth of the global ligases enzyme market. In addition, surge in R&D investments to develop ligases as therapeutic interventions of cancer fuels the market growth. However, high sensitivity of the enzyme to factors such as DNA concentration, ligase concentration, temperature, and buffer composition affect limits its adoption, thereby restraining the market growth.

Based on source, the global ligase enzyme market is segmented into microorganism, animal, and plant. Depending on end user, it is bifurcated into diagnostic center & hospital and research institute. Region wise, it is studied across North America (U.S., Canada, and Mexico), Europe (Germany, France, the UK, Italy, Spain, and rest of Europe), Asia-Pacific (Japan, China, Australia, India, South Korea, and rest of Asia-Pacific), and LAMEA (Brazil, Saudi Arabia, South Africa, and rest of LAMEA).

Market dynamics

Drivers

Increase in research activities across the globe
Rise in incidence of birth genetic disorders and infectious diseases
Surge in R&D investments to develop ligases as targets for therapeutic intervention of cancer

Restraint

High sensitivity of enzymes to temperature & pH

Market players

The major players profiled in the report include Novozymes A/S, Koninklijke DSM N.V., DowDuPont Inc., BASF SE, Advanced Enzyme Technologies Ltd., AB Enzymes GmbH, Codexis, Inc., Amano Enzyme, F. Hoffmann-La Roche Ltd., and Thermo Fisher Scientific Inc.

KEY TAKEAWAYS

MARKET LANDSCAPE

By Source

Microorganism
Animal
Plant

By End User

Diagnostic Center & Hospital
Research Institute

By Region

North America
- U.S.
- Canada
- Mexico
Europe
- Germany
- UK
- France
- Spain
- Italy
- Rest of Europe
Asia-Pacific
- Japan
- China
- Australia
- India
- South Korea
- Rest of Asia-Pacific
LAMEA
- Brazil
- Saudi Arabia
- South Africa
- Rest of LAMEA

SECTION 1 EXECUTIVE SUMMARY
1.1. KEY FINDINGS
1.2. MARKET ATTRACTIVENESS AND TREND ANALYSIS
1.3. COMPETITIVE LANDSCAPE AND RECENT INDUSTRY DEVELOPMENT ANALYSIS
SECTION 2 INTRODUCTION
2.1. REPORT DESCRIPTION
2.2. SCOPE AND DEFINITIONS
2.3. RESEARCH METHODOLOGY
SECTION 3 MARKET LANDSCAPE
3.1. GROWTH DRIVERS
3.1.1. Impact Analysis
3.2. RESTRAINS AND CHALLENGES
3.2.1. Impact Analysis
3.3. PORTERS ANALYSIS
3.3.1. Bargaining power of buyers
3.3.2. Bargaining power of suppliers
3.3.3. Threat of substitutes
3.3.4. Industry rivalry
3.3.5. Threat of new entrants
3.4. GLOBAL LIGASE ENZYMES TECHNOLOGIES MARKET SHARES ANALYSIS, 2014-2025
3.4.1. Global ligase enzymes technologies market share by source, 2014-2025
3.4.2. Global ligase enzymes technologies market share by end user, 2014-2025
3.4.3. Global ligase enzymes technologies market share by geography, 2014-2025
SECTION 4 LIGASE ENZYMES MARKET BY SOURCE
4.1. MICROORGANISM
4.1.1. Historical Market Size by Region, 2014-2016
4.1.2. Market Forecast by Region, 2017-2025
4.2. ANIMAL
4.2.1. Historical Market Size by Region, 2014-2016
4.2.2. Market Forecast by Region, 2017-2025
4.3. PLANT
4.3.1. Historical Market Size by Region, 2014-2016
4.3.2. Market Forecast by Region, 2017-2025
SECTION 5 LIGASE ENZYMES MARKET BY END USER
5.1. DIAGNOSTIC CENTER AND HOSPITALS
5.1.1. Historical Market Size by Region, 2014-2016
5.1.2. Market Forecast by Region, 2017-2025
5.2. RESEARCH INSTITUTES
5.2.1. Historical Market Size by Region, 2014-2016
5.2.2. Market Forecast by Region, 2017-2025
SECTION 6 LIGASE ENZYMES MARKET BY GEOGRAPHY
6.1. NORTH AMERICA
6.1.1. U.S.
6.1.1.1. Historical Market Size, 2014-2016
6.1.1.2. Market Forecast, 2017-2025
6.1.2. Canada
6.1.2.1. Historical Market Size, 2014-2016
6.1.2.2. Market Forecast, 2017-2025
6.1.3. Mexico
6.1.3.1. Historical Market Size, 2014-2016
6.1.3.2. Market Forecast, 2017-2025
6.2. EUROPE
6.2.1. Germany
6.2.1.1. Historical Market Size, 2014-2016
6.2.1.2. Market Forecast, 2017-2025
6.2.2. UK
6.2.2.1. Historical Market Size, 2014-2016
6.2.2.2. Market Forecast, 2017-2025
6.2.3. France
6.2.3.1. Historical Market Size, 2014-2016
6.2.3.2. Market Forecast, 2017-2025
6.2.4. Spain
6.2.4.1. Historical Market Size, 2014-2016
6.2.4.2. Market Forecast, 2017-2025
6.2.5. Italy
6.2.5.1. Historical Market Size, 2014-2016
6.2.5.2. Market Forecast, 2017-2025
6.2.6. Rest of Europe
6.2.6.1. Historical Market Size, 2014-2016
6.2.6.2. Market Forecast, 2017-2025
6.3. ASIA PACIFIC
6.3.1. Japan
6.3.1.1. Historical Market Size, 2014-2016
6.3.1.2. Market Forecast, 2017-2025
6.3.2. China
6.3.2.1. Historical Market Size, 2014-2016
6.3.2.2. Market Forecast, 2017-2025
6.3.3. India
6.3.3.1. Historical Market Size, 2014-2016
6.3.3.2. Market Forecast, 2017-2025
6.3.4. Australia
6.3.4.1. Historical Market Size, 2014-2016
6.3.4.2. Market Forecast, 2017-2025
6.3.5. South Korea
6.3.5.1. Historical Market Size, 2014-2016
6.3.5.2. Market Forecast, 2017-2025
6.3.6. Rest of Asia-Pacific
6.3.6.1. Historical Market Size, 2014-2016
6.3.6.2. Market Forecast, 2017-2025
6.4. LAMEA
6.4.1. Brazil
6.4.1.1. Historical Market Size, 2014-2016
6.4.1.2. Market Forecast, 2017-2025
6.4.2. Saudi Arabia
6.4.2.1. Historical Market Size, 2014-2016
6.4.2.2. Market Forecast, 2017-2025
6.4.3. South Africa
6.4.3.1. Historical Market Size, 2014-2016
6.4.3.2. Market Forecast, 2017-2025
6.4.4. Rest of LAMEA
6.4.4.1. Historical Market Size, 2014-2016
6.4.4.2. Market Forecast, 2017-2025
SECTION 7 COMPANY PROFILES
7.1. NOVOZYMES AS
7.1.1. Overview
7.1.2. Financials and business segments
7.1.3. Recent Developments
7.2. KONINKLIJKE DSM N.V.
7.2.1. Overview
7.2.2. Financials and business segments
7.2.3. Recent Developments
7.3. DOWDUPONT INC.
7.3.1. Overview
7.3.2. Financials and business segments
7.3.3. Recent Developments
7.4. BASF SE
7.4.1. Overview
7.4.2. Financials and business segments
7.4.3. Recent Developments
7.5. ADVANCED ENZYME TECHNOLOGIES LTD.
7.5.1. Overview
7.5.2. Financials and business segments
7.5.3. Recent Developments
7.6. AB ENZYMES GMBH
7.6.1. Overview
7.6.2. Financials and business segments
7.6.3. Recent Developments
7.7. CODEXIS, INC.
7.7.1. Overview
7.7.2. Financials and business segments
7.7.3. Recent Developments
7.8. AMANO ENZYME
7.8.1. Overview
7.8.2. Financials and business segments
7.8.3. Recent Developments
7.9. F. HOFFMANN-LA ROCHE LTD.
7.9.1. Overview
7.9.2. Financials and business segments
7.9.3. Recent Developments
7.10. THERMO FISHER SCIENTIFIC INC.
7.10.1. Overview
7.10.2. Financials and business segments
7.10.3. Recent Developments

List of Tables

TABLE 1. LIGASE ENZYMES MARKET VALUE FOR SOURCE, BY REGION, 2017-2025, $MILLION
TABLE 2. LIGASE ENZYMES MARKET VALUE FOR END USER, BY REGION, 2017-2025, $MILLION
TABLE 3. LIGASE ENZYMES MARKET VALUE FOR DIAGNOSTIC CENTER AND HOSPITALS, BY REGION, 2017-2025, $MILLION
TABLE 4. LIGASE ENZYMES MARKET VALUE FOR RESEARCH INSTITUTES, BY REGION, 2017-2025, $MILLION
TABLE 5. LIGASE ENZYMES MARKET VALUE FOR NORTH AMERICA, BY COUNTRY, 2014-2025, $MILLION
TABLE 6. LIGASE ENZYMES MARKET VALUE FOR NORTH AMERICA, BY SOURCE, 2014-2025, $MILLION
TABLE 7. LIGASE ENZYMES MARKET VALUE FOR NORTH AMERICA, BY END USER, 2014-2025, $MILLION
TABLE 8. LIGASE ENZYMES MARKET VALUE FOR EUROPE, BY COUNTRY, 2014-2025, $MILLION
TABLE 9. LIGASE ENZYMES MARKET VALUE FOR EUROPE, BY SOURCE, 2014-2025, $MILLION
TABLE 10. LIGASE ENZYMES MARKET VALUE FOR EUROPE, BY END USER, 2014-2025, $MILLION
TABLE 11. LIGASE ENZYMES MARKET VALUE FOR ASIA PACIFIC, BY COUNTRY, 2014-2025, $MILLION
TABLE 12. LIGASE ENZYMES MARKET VALUE FOR ASIA PACIFIC, BY SOURCE, 2014-2025, $MILLION
TABLE 13. LIGASE ENZYMES MARKET VALUE FOR ASIA PACIFIC, BY END USER, 2014-2025, $MILLION
TABLE 14. LIGASE ENZYMES MARKET VALUE FOR LAMEA, BY COUNTRY, 2014-2025, $MILLION
TABLE 15. LIGASE ENZYMES MARKET VALUE FOR LAMEA, BY SOURCE, 2014-2025, $MILLION
TABLE 16. LIGASE ENZYMES MARKET VALUE FOR LAMEA, BY END USER, 2014-2025, $MILLION
TABLE 17. NOVOZYMES AS - COMPANY SNAPSHOT
TABLE 18. KONINKLIJKE DSM N.V. - COMPANY SNAPSHOT
TABLE 19. DOWDUPONT INC. - COMPANY SNAPSHOT
TABLE 20. BASF SE - COMPANY SNAPSHOT
TABLE 21. ADVANCED ENZYME TECHNOLOGIES LTD. - COMPANY SNAPSHOT
TABLE 22. AB ENZYMES GMBH - COMPANY SNAPSHOT
TABLE 23. CODEXIS, INC. - COMPANY SNAPSHOT
TABLE 24. AMANO ENZYME - COMPANY SNAPSHOT
TABLE 25. F. HOFFMANN-LA ROCHE LTD. - COMPANY SNAPSHOT
TABLE 26. THERMO FISHER SCIENTIFIC INC. - COMPANY SNAPSHOT

List of Figures

FIGURE 1. LIGASE ENZYMES: DIAGNOSTIC CENTER AND HOSPITALS MARKET VALUE, 2014-2016, $MILLION
FIGURE 2. LIGASE ENZYMES: RESEARCH INSTITUTES MARKET VALUE, 2014-2016, $MILLION
FIGURE 3. LIGASE ENZYMES: NORTH AMERICA MARKET VALUE, 2014-2016, $MILLION
FIGURE 4. LIGASE ENZYMES: U.S. MARKET VALUE, 2014-2016, $MILLION
FIGURE 5. LIGASE ENZYMES: CANADA MARKET VALUE, 2014-2016, $MILLION
FIGURE 6. LIGASE ENZYMES: MEXICO MARKET VALUE, 2014-2016, $MILLION
FIGURE 7. LIGASE ENZYMES: EUROPE MARKET VALUE, 2014-2016, $MILLION
FIGURE 8. LIGASE ENZYMES: GERMANY MARKET VALUE, 2014-2016, $MILLION
FIGURE 9. LIGASE ENZYMES: UK MARKET VALUE, 2014-2016, $MILLION
FIGURE 10. LIGASE ENZYMES: FRANCE MARKET VALUE, 2014-2016, $MILLION
FIGURE 11. LIGASE ENZYMES: SPAIN MARKET VALUE, 2014-2016, $MILLION
FIGURE 12. LIGASE ENZYMES: ITALY MARKET VALUE, 2014-2016, $MILLION
FIGURE 13. LIGASE ENZYMES: REST OF EUROPE MARKET VALUE, 2014-2016, $MILLION
FIGURE 14. LIGASE ENZYMES: ASIA PACIFIC MARKET VALUE, 2014-2016, $MILLION
FIGURE 15. LIGASE ENZYMES: JAPAN MARKET VALUE, 2014-2016, $MILLION
FIGURE 16. LIGASE ENZYMES: CHINA MARKET VALUE, 2014-2016, $MILLION
FIGURE 17. LIGASE ENZYMES: INDIA MARKET VALUE, 2014-2016, $MILLION
FIGURE 18. LIGASE ENZYMES: AUSTRALIA MARKET VALUE, 2014-2016, $MILLION
FIGURE 19. LIGASE ENZYMES: SOUTH KOREA MARKET VALUE, 2014-2016, $MILLION
FIGURE 20. LIGASE ENZYMES: REST OF ASIA-PACIFIC MARKET VALUE, 2014-2016, $MILLION
FIGURE 21. LIGASE ENZYMES: LAMEA MARKET VALUE, 2014-2016, $MILLION
FIGURE 22. LIGASE ENZYMES: BRAZIL MARKET VALUE, 2014-2016, $MILLION
FIGURE 23. LIGASE ENZYMES: SAUDI ARABIA MARKET VALUE, 2014-2016, $MILLION
FIGURE 24. LIGASE ENZYMES: SOUTH AFRICA MARKET VALUE, 2014-2016, $MILLION
FIGURE 25. LIGASE ENZYMES: REST OF LAMEA MARKET VALUE, 2014-2016, $MILLIO

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